In short
Isolated from rabbit blood in 1977 and named for sleep, but a 2006 review called the sleep link "extremely poorly documented". Health Canada lists it among seized unauthorized peptides.
Also known asDSIP
CategoryBrain & sleep
Canada statusNot authorized in Canada
Human evidence Very limited: almost all animal or cell studies
Last reviewedNovember 10, 2026
How strong is the human evidence?
- Cell & animal
- Small human studies
- Some randomized trials
- Large randomized trials
What is DSIP?
DSIP is a short peptide first isolated in 1977. Its gene, precursor protein and receptor have not been identified (Kovalzon & Strekalova 2006).
Is DSIP legal in Canada?
Not authorized. Named in Health Canada's April 2026 advisory among seized unauthorized injectable peptides.
What the research shows
- Various effects in lab studies; certain DSIP analogs (not DSIP itself) promoted slow-wave sleep in rabbits and rats.
What it doesn't show
- No good human evidence that DSIP improves sleep.
Common questions
Does DSIP help you sleep?
The sleep link is weakly documented, even in animals.
Is DSIP legal in Canada?
No. Health Canada lists it among seized unauthorized peptides.
Sources
- Health Canada — Peptides: Overview
- Health Canada advisory RA-81874 (Apr 9, 2026): Think twice before injecting peptides bought online
- Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem 2006
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