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Growth hormone

GHRP-2 and GHRP-6

Not authorized in Canada Evidence 2/4
GHRP-2 and GHRP-6 peptide structure illustration (abstract amino-acid chain)
In short

Synthetic growth hormone-releasing peptides whose study led to the discovery of the natural hormone ghrelin. Not authorized in Canada.

Reviewed November 10, 2026 · 5 sources cited below

Also known asgrowth hormone-releasing peptides
Canada statusNot authorized in Canada
Human evidence Limited: small or low-quality human studies
Sport (WADA)WADA's Prohibited List bans growth hormone releasing factors and secretagogues (S2) at all times.
Last reviewedNovember 10, 2026

How strong is the human evidence?

Limited: small or low-quality human studies. How we rate evidence

What is GHRP-2 and GHRP-6?

GHRPs are small synthetic peptides that trigger GH release through the receptor later found to respond to ghrelin. Cyril Bowers, who developed them, reviewed this history (1998, 2001).

GHRP-6 is known for increasing appetite. Both are sold online as "research peptides".

What the research shows

  • Human pharmacology studies show acute GH release (reviewed by Bowers 1998; Ghigo et al. 1997).

What it doesn't show

  • No randomized trials showing muscle, fat-loss or recovery benefits in healthy adults.

Common questions

GHRP-2 vs GHRP-6?

Both release GH; GHRP-6 is more associated with hunger. Neither is authorized in Canada.

Are GHRPs legal in Canada?

They are not authorized by Health Canada.

Sources

  1. Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci 1998
  2. Bowers CY. Unnatural growth hormone-releasing peptide begets natural ghrelin. JCEM 2001
  3. Ghigo E et al. Growth hormone-releasing peptides. Eur J Endocrinol 1997
  4. Health Canada Drug Product Database (searched Nov 10, 2026)
  5. World Anti-Doping Agency — Prohibited List

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